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The Institute has an Operating Committee and an Advisory Board both at this time consisting only of Johns Hopkins-affiliated personnel.

As of September 2005:

Chi Van Dang, M.D., Ph.D., Chair of Advisory and Operating Committees
Vice Dean for Research, The Johns Hopkins University School of Medicine
Professor, Department of Medicine

Aravinda Chakravarti, Ph.D.
Professor and Director, McKusick-Nathans Institute for Genetic Medicine, JHUSOM

Ted Dawson, M.D., Ph.D.
Professor, Departments of Neurology and Neuroscience

Valina Dawson, Ph.D.
Vice Chair, Department of Neurology
Professor, Departments of Neurology, Neuroscience, and Physiology

Stephen V. Desiderio, M.D., Ph.D.
Professor, Department of Molecular Biology & Genetics

John D. Gearhart, Ph.D.
Professor, Departments of Gynecology & Obstetrics, Physilogy, and Comparative Medicine

John Griffin, M.D.
Professor and Director, Department of Neurology, JHUSOM

Abraham (Avi) Kupfer, Ph.D.
Professor, Department of Cell Biology

Murray B. Sachs, Ph.D.
Professor and Director, Department of Biomedical Engineering, JHU/JHUSOM

Gregg L. Semenza, M.D., Ph.D.
Director, Vascular Biology Program, ICE
Professor of Pediatrics, Medicine, Oncology, Radiation Oncology, and McKusick-Nathan's Institute of Genetic Medicine

Bert Vogelstein, M.D.
Professor, Department of Oncology, The Kimmel Cancer Center at Johns Hopkins

Myron L. Weisfeldt, M.D.
Professor and Director, Department of Medicine, JHUSOM