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The Institute has an Operating Committee and an Advisory Board both at this time consisting only of Johns Hopkins-affiliated personnel.

As of February 2008:

Chi Van Dang, M.D., Ph.D.,
Chair of Advisory and Operating CommitteesVice Dean for Research,
The Johns Hopkins University School of Medicine Professor, Department of Medicine

Ted Dawson, M.D., Ph.D.
Professor, Departments of Neurology and Neuroscience

Valina Dawson, Ph.D.
Vice Chair, Department of Neurology
Professor, Departments of Neurology, Neuroscience, and Physiology

Stephen V. Desiderio, M.D., Ph.D.
Professor, Department of Molecular Biology & Genetics

Abraham (Avi) Kupfer, Ph.D.
Professor, Department of Cell Biology

Kai Sauer, M.S.
Administrator, Institute for Cell Engineering (ICE)

Gregg L. Semenza, M.D., Ph.D.
Director, Vascular Biology Program, ICE
Professor of Pediatrics, Medicine, Oncology, Radiation Oncology, and McKusick-Nathan's Institute of Genetic Medicine