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Immunobiology Program
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Selected Publications

Lieping Chen | Stephen Desiderio | Abraham Kupfer | Joel Pomerantz

Lieping Chen

Dong H, Zhu G, Tamada K, Flies DB, van Deursen JMA and Chen L. (2004) Director, Dermatology Research. Immunity 276:26421 [PubMed]

Chen L. (2004) Director, Dermatology Research. Nat. Rev. Immunol. 1:463 [PubMed]

Sica GL, Choi IH, Zhu G, Tamada K, Wang S, Tamura H, Chapoval AI, Flies DB, Bajorath J and Chen L. (2003) Director, Dermatology Research. Immunity 21:3935 [PubMed]

Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, Roche PC, Lu J, Zhu G, Tamada K, Lennon VA, Celis E and Chen L. (2002) Director, Dermatology Research. Nature Medicine 276:27806 [PubMed]

Chapoval AI, Ni J, Lau JS, Wilcox RA, Flies DB, Dong H, Sica GL, Zhu G, Tamada K and Chen L. (2001) Director, Dermatology Research. Nature Immunol. 108:331 [PubMed]

Tamada K, Shimozaki K, Chapoval AI, Zhu G, Sica G, Flies D, Boone T, Hsu H, Fu YX, Nagata S, Ni J and Chen L. (2000) Director, Dermatology Research. Nature Medicine 16:545-9 [PubMed]

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Stephen Desiderio

Lin, W.-C., and Desiderio, S. (1993). Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation. Science 260, 953-959.
PubMed Abstract

Lin, W.-C., and Desiderio, S. (1994). Cell cycle regulation of the V(D)J recombination activating protein RAG-2. Proc. Natl. Acad. Sci. USA. 91, 2733-2737.
PubMed Abstract

Li, Z., Dordai, D. Lee, J., and Desiderio, S. (1996). A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle. Immunity. 5, 575-589.
PubMed Abstract

Yang, W., and Desiderio, S. (1997) BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement. Proc. Natl. Acad .Sci. USA 94, 604-609.
PubMed Abstract

Li, W., Swanson, P., and Desiderio, S. (1997) RAG-1 and RAG-2 dependent assembly of functional complexes with V(D)J recombination substrates in solution. Mol. Cell. Biol. 17, 6932-6939.
PubMed Abstract

Malek, S.N., Dordai, D.I., Rein, J., Dintzis, H., and Desiderio, S. (1998) Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase. Proc. Natl. Acad. Sci. USA 95, 7351-7356.
PubMed Abstract

Swanson, P.C., and Desiderio, S. (1998) V(D)J recombination signal recognition: Distinct, overlapping DNA-protein contacts in complexes containing RAG-1 with and without RAG-2. Immunity 9,115-125.
PubMed Abstract

Swanson, P.C., and Desiderio, S. (1999) RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex. Mol. Cell. Biol. 19, 3674-3683.
PubMed Abstract

Lee, J., and Desiderio, S. (1999) Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair. Immunity 11, 771-781.
PubMed Abstract

Desiderio, S. and Lee, J. (2000) Signalling pathways that control V(D)J recombination. Curr.. Topics Microbiol. Immunol. 245, 31-56.
PubMed Abstract

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Abraham Kupfer

Kupfer, A. and Kupfer, H. (2003) Co-Director, Program in Immunology at ICE. Seminars in Immunology 19:4712-4722 [PubMed]

Freiberg, B. A., Kupfer, H., Maslanik, W., Delli, J., Kappler, J., Zaller, D.M. and Kupfer, A. (2002) Co-Director, Program in Immunology at ICE. Nat. Immunol. 18:6201–6208 [PubMed]

Potter, T.A., K. Grebe, B. Freiberg, and Kupfer, A. (2001) Co-Director, Program in Immunology at ICE. Proc. Natl. Acad. Sci. USA 92:819–828 [PubMed]

Kupfer, A. (2000) Co-Director, Program in Immunology at ICE. Nature Medicine 16:2248–2254 [PubMed]

Monks, C.R.F., B.A. Freiberg, H. Kupfer, N. Sciaky, and Kupfer, A. (1998) Co-Director, Program in Immunology at ICE. Nature 166:4773-4779 [PubMed]

Monks, C.R.F., Kupfer, H., Tamir, I., Barlow, A., and Kupfer, A. (1997) Co-Director, Program in Immunology at ICE. Nature 46 (Suppl): S67-S72 [PubMed]

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Joel Pomerantz

Rothenberg, M.E., J.L. Pomerantz, W.F. Owen, Jr., S. Avraham, R.J. Soberman, K.F. Austen, and R.L. Stevens. (1988) Characterization of a human eosinophil proteoglycan, and augmentation of its biosynthesis and size by interleukin 3, interleukin 5, and granulocyte/macrophage colony stimulating factor. Journal of Biological Chemistry 263, 13901-13908.
PubMed Reference

Pomerantz, J.L., F. Mauxion, M. Yoshida, W.C. Greene, and R. Sen. (1989) A second sequence element located 3' to the NF-kB binding site regulates IL-2 receptor-alpha gene induction. Journal of Immunology 143, 4275-4281.
PubMed Reference

Pomerantz, J.L., T.M. Kristie, and P.A. Sharp. (1992) Recognition of the surface of a homeo domain protein. Genes & Development 6, 2047-2057.
PubMed Reference

Pomerantz, J.L., and P.A. Sharp. (1994) Homeodomain determinants of major groove recognition. Biochemistry, 33, 10851-10858.
PubMed Reference

Kristie, T.M., J.L. Pomerantz, T.C. Twomey, S.A. Parent, And P.A. Sharp. (1995) The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides. Journal of Biological Chemistry, 270, 4387-4394.
PubMed Reference

Pomerantz, J.L., P.A. Sharp, and C.O. Pabo. (1995) Structure-based design of transcription factors. Science, 267, 93-96.
PubMed Reference

Pomerantz, J.L., C.O. Pabo, and P.A. Sharp. (1995) Analysis of homeodomain function by structure-based design of a transcription factor. Proc. Natl. Acad. Sci.USA, 92, 9752-9756.
PubMed Reference

Pomerantz, J.L., S.A. Wolfe, and C.O. Pabo. (1998) Structure-based design of a dimeric zinc finger protein. Biochemistry, 37, 965-970.
PubMed Reference

Pomerantz, J.L. and D. Baltimore. (1999) NF-kB activation by a signaling complex containing TRAF2, TANK, and TBK1, a novel IKK-related kinase. EMBO J., 18, 6694-6704.
PubMed Reference

Pomerantz, J.L. and D. Baltimore. (2000) Signal transduction – A cellular rescue team. Nature, 406, 26-29.
PubMed Reference

Wurtz, N.R., J.L. Pomerantz, D. Baltimore, and P.B. Dervan. (2002) Inhibition of DNA binding by NF-kB with pyrrole-imidazole polyamides. Biochemistry, 41, 7604-7609.
PubMed Reference

Pomerantz, J.L., and D. Baltimore. (2002) Two pathways to NF-kB. Mol. Cell, 10, 693-695.
PubMed Reference

Pomerantz, J.L., E.M. Denny, and D. Baltimore. (2002) CARD11 mediates factor-specific activation of NF-kB by the T cell receptor complex. EMBO J., 21, 5184-5194.
PubMed Reference


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