Linzhao Cheng  |  John Gearhart

Linzhao Cheng

Cheng L , Hammond H, Ye Z, Zhan X, and Dravid G (2003). Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture. Stem Cells, 21:131-142.

Angelopoulou M, Novelli E, Grove JE, Henry M. Rinder M, Civin C, Cheng L, Krause DS (2003). Cotransplantation Of Human Mesenchymal Stem Cells Enhances Human Myelopoiesis And Megakaryocytopoiesis In NOD/SCID Mice. Experimental Hematology, 7: 413-420.

Yu X, Zhan X, D’Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI and Cheng L (2003). Lentiviral Vectors with Two Independent Internal Promoters Transfer High-Level Expression of Multiple Transgenes to Human Hematopoietic Stem-Progenitor Cells. Molecular Therapy, 7: 827-838.

McCauslin CS, Wine J, Cheng L, Klarmann KD, Candotti F, Clausen PA, Spence SE, Keller JR (2003). In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knockout animals. Blood, 102: 843-848.

Cui Y, Kelleher E, Straley E, Fuchs E, Gorski K, Levitsky H, Borrello I, Civin C, Schoenberger S, Cheng L, Pardoll DM, Whartenby KA. (2003). Immunotherapy of established tumors using bone marrow transplantation with antigen gene-modified hematopoietic stem cells. Nature Medicine, 9: 952-958.

Zhou X, Cui Y, Huang X, Yu Z, Pardoll DM, Jaffee EM, and Cheng L (2003). Lentivirus-Mediated Gene Transfer and Expression in Established Human Cytotoxic T cells Specific to Tumor antigen and Primary Unstimulated T Cells. Human Gene Therapy, 14: 1089-1105.

Pan F, Ye Z, Cheng L and Liu JO (2004). MEF-2 mediates calcium-dependent activation of the interleukin-2 gene in T lymphocytes. Journal of Biological Chemistry. 279: 14477-14480.

Dunlap S, Yu X, Cheng L, Civin CI, Alani RM (2004). High-Efficiency Stable Gene Transduction in Primary Human Melanocytes Using a Lentiviral Expression System. J Invest Dermatol. 122: 549-551.

Zhan X, Dravid G, Ye Z, Hammond H, Shamblott M, Gearhart J, and Cheng L (2004). Functional antigen-presenting leukocytes derived from human embryonic stem cells in vitro. The Lancet, 363: 163-171.

Chen HH, Zhan X, Kumar A, Du X, Wang D, Cheng L, Yang X (2004).Detection of Dual Gene Expression in Arteries Using an Optical Imaging Method. J. Biomedical Optics 9(6):1223-1229.

Du, X, Qiu B, Zhan X, Kolmakova A, Gao F, Hofmann LV, Cheng L, Chatterjee S, Yang XM (2005). Intravascular MR/Radiofrequency-Enhanced Vascular Gene Transduction/Expression: Feasibility Study in Pigs. Radiology 236: 939-944.

Chou W-C, Chen H-Y, Yu S-L , Cheng L, Yang P-C, Dang CV (2005). Arsenic suppresses gene expression in promyelocytic leukemia cells partly through SP1 o xidation. Blood, 106: 304-310.

Dravid G, Ye Z, Hammond H, Chen G, Pyle A, Donovan PJ, Yu X and Cheng L (2005). Defining the role of Wnt/beta-catenin signaling in the survival, proliferation and self-renewal of human embryonic stem cells . Stem Cells, 23: 1489-1501.

Wang K, Xue T, Tsang SY, Van Huizen R, Wong CW, Lai KW, Ye Z, Cheng L, Au KW, Zhang J, Li GR, Lau CP, Tse HF, Li RA (2005). Electrophysiological properties of pluripotent human and mouse embryonic stem cells. Stem Cells, 23: 1526-1534.

Yu X, Alder JK, Chun JH, Alan D Friedman AD, Heimfeld S, Cheng L, Civin CI (2006). HES1 inhibits cycling of hematopoietic progenitor cells via DNA-binding. Stem Cells, 24: 876-888.

Litvinov IV, Antony L, Dalrymple SL, Becker R, Cheng L, Isaacs JT (2006). C3, but not DU145, human prostate cancer cells retain the coregulators required for tumor suppressor ability of androgen receptor. The Prostate, July 11, online.

Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions. Cai L, Ye, Z, Zhou, BY, Dravid G, Mali P, Zhou C and Cheng L. Cell Research, in press.

John Gearhart

Shamblott,MJ, Axelman, J., Wang, S., Bugg, EM, Littlefield, JW., Donovan, PJ., Blumenthal, PD., Huggins, GR., and Gearhart, JD., Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc Natl Acad Sci USA 95:13726-13731, 1998.

Gearhart JD. New potential for human embryonic germ cells. Science 282:1061-1062, 1999.

Solter D and Gearhart JD. Putting stem cells to work. Science 283:1468-1470, 1999.

Shamblott MJ, Axelman J, Littlefield JW, Blumenthal PD, Huggins GR, Cui Y, Cheng L, Gearhart JD. Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):113-8.

Donovan PJ, Gearhart JD. The end of the beginning for pluripotent stem cells. Nature 414, 92 - 97 (2001)

Moran TH, Capone GT, Knipp S, Davisson MT, Reeves RH, Gearhart JD. The effects of piracetam on cognitive performance in a mouse model of Down's syndrome. Physiol Behav 2002 Nov;77(2-3):403-9.

Shih IeM, Hsu MY, Oldt RJ 3rd, Herlyn M, Gearhart JD, Kurman RJ. The Role of E-cadherin in the Motility and Invasion of Implantation Site Intermediate Trophoblast. Placenta 2002 Nov;23(10):706-15.

Shamblott MJ, Bugg EM, Lawler AM, Gearhart JD. Craniofacial abnormalities resulting from targeted disruption of the murine Sim2 gene. Dev Dyn 2002 Aug;224(4):373-80.

Onyango P, Jiang S, Uejima H, Shamblott MJ, Gearhart JD, Cui H, Feinberg AP. Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages. Proc Natl Acad Sci U S A 2002 Aug 6;99(16):10599-604.